Scientific Publications
Every year Maurice Wilkins Centre investigators produce a large number of peer-reviewed scientific papers and reviews published in international journals. Research directly supported by the Maurice Wilkins Centre generated the following scientific papers.
2024
Abolins-Thompson, H., Henare, K. L., Simonson, B., Chaffin, M., Ellinor, P. T., Henry, C., Haimona, M., Aitken, J., Parai, T., Elkington, B., Rongo, M., Danielson, K. M. & Leask, M. P. (2024). Culturally responsive strategies and practical considerations for live tissue studies in Māori participant cohorts. Frontiers in Research Metrics and Analytics 9. https://doi.org/10.3389/frma.2024.1468400
Adolph, C., Cheung, C. Y., McNeil, M. B., Jowsey, W. J., Williams, Z. C., Hards, K., Harold, L. K., Aboelela, A., Bujaroski, R. S., Buckley, B. J., Tyndall, J. D. A., Li, Z., Langer, J. D., Preiss, L., Meier, T., Steyn, A. J. C., Rhee, K. Y., Berney, M., Kelso, M. J. & Cook, G. M. (2024). A dual-targeting succinate dehydrogenase and F1Fo-ATP synthase inhibitor rapidly sterilizes replicating and non-replicating Mycobacterium tuberculosis. Cell Chemical Biology 31(4): 683-698.e687. https://doi.org/10.1016/j.chembiol.2023.12.002
Adolph, C., Hards, K., Williams, Z. C., Cheung, C. Y., Keighley, L. M., Jowsey, W. J., Kyte, M., Inaoka, D. K., Kita, K., Mackenzie, J. S., Steyn, A. J., Li, Z., Yan, M., Tian, G. B., Zhang, T., Ding, X., Furkert, D. P., Brimble, M. A., Hickey, A. J., McNeil, M. B. & Cook, G. M. (2024). Identification of Chemical Scaffolds That Inhibit the Mycobacterium tuberculosis Respiratory Complex Succinate Dehydrogenase. ACS Infectious Diseases 10(10): 3496-3515. https://doi.org/10.1021/acsinfecdis.3c00655
Aguilar, C. J., Sarwar, M., Brimble, M. A. & Kavianinia, I. (2024). N-Substituted Iminothiolane (NIT): A Promising Strategy for Protecting Lysine Side Chains for Solid-Phase Peptide Chemistry. Organic Letters. https://doi.org/10.1021/acs.orglett.4c03389
Ahangarpour, M., Brimble, M. A. & Kavianinia, I. (2024). Late-Stage Desulfurization Enables Rapid and Efficient Solid-Phase Synthesis of Cathepsin-Cleavable Linkers for Antibody-Drug Conjugates. Bioconjugate Chemistry 35(7): 1007-1014. https://doi.org/10.1021/acs.bioconjchem.4c00199
Ajithkumar, P., Gimenez, G., Stockwell, P. A., Almomani, S., Bowden, S. A., Leichter, A. L., Ahn, A., Pattison, S., Schmeier, S., Frizelle, F. A., Eccles, M. R., Purcell, R. V., Rodger, E. J. & Chatterjee, A. (2024). DNA methylome and transcriptome maps of primary colorectal cancer and matched liver metastasis. Data 9(1). https://doi.org/10.3390/data9010008
Ashina, H., Christensen, R. H., Hay, D. L., Pradhan, A. A., Hoffmann, J., Reglodi, D., Russo, A. F. & Ashina, M. (2024). Pituitary adenylate cyclase-activating polypeptide signalling as a therapeutic target in migraine. Nature Reviews Neurology 20(11): 660-670. https://doi.org/10.1038/s41582-024-01011-4
Ashina, M., Hoffmann, J., Ashina, H., Hay, D. L., Flores-Montanez, Y., Do, T. P., De Icco, R. & Dodick, D. W. (2024). Pharmacotherapies for migraine and translating evidence from bench to bedside. Mayo Clinic Proceedings 99(2): 285-299. https://doi.org/10.1016/j.mayocp.2023.07.003
Babych, M., Garelja, M. L., Nguyen, P. T., Hay, D. L. & Bourgault, S. (2024). Converting the amyloidogenic islet amyloid polypeptide into a potent nonaggregating peptide ligand by side chain-to-side chain macrocyclization. Journal of the American Chemical Society 146(37): 25513-25526. https://doi.org/10.1021/jacs.4c05297
Baleivanualala, S. C., Matanitobua, S., Samisoni, Y., Soqo, V., Smita, S., Mailulu, J., Nabose, I., Lata, A., Shayam, C., Sharma, R., Wilson, D., Crump, J. A. & Ussher, J. E. (2024). Environmental contamination with carbapenem resistant Acinetobacter baumannii in healthcare settings in Fiji: a potential source of infection. Frontiers in Cellular and Infection Microbiology 14. https://doi.org/10.3389/fcimb.2024.1429443
Bashiri, G., Bulloch, E. M. M., Bramley, W. R., Davidson, M., Stuteley, S. M., Young, P. G., Harris, P. W. R., Naqvi, M. S. H., Middleditch, M. J., Schmitz, M., Chang, W. C., Baker, E. N. & Squire, C. J. (2024). Poly-γ-glutamylation of biomolecules. Nature Communications 15(1). https://doi.org/10.1038/s41467-024-45632-1
Blud, D., Rubio-Reyes, P., Perret, R. & Weinkove, R. (2024). Tuning CAR T-cell therapies for efficacy and reduced toxicity. Semin Hematol 61(5): 333-344. https://doi.org/10.1053/j.seminhematol.2024.07.003
Burn, O. K., Dasyam, N. & Hermans, I. F. (2024). Recruiting natural killer t cells to improve vaccination: Lessons from preclinical and clinical studies. Critical Reviews in Oncogenesis 29(1): 31-43. https://doi.org/10.1615/critrevoncog.2023049407
Drummond, G. J., Grant, P. S., Geurts, A. M., Furkert, D. P. & Brimble, M. A. (2024). Synthesis of the bicyclic butenolide core of pallamolide A: a biomimetic approach. Organic and Biomolecular Chemistry 22(39): 8032-8036. https://doi.org/10.1039/D4OB01380H
Eade, L., Sullivan, M. P., Allison, T. M., Goldstone, D. C. & Hartinger, C. G. (2024). Not all binding sites are equal: Site determination and folding state analysis of gas-phase protein-metallodrug adducts. Chemistry - A European Journal 30(28). https://doi.org/10.1002/chem.202400268
Engelhardt, P. M., Keyzers, R. & Brimble, M. A. (2024). Histidine-bridged cyclic peptide natural products: isolation, biosynthesis and synthetic studies. Organic and Biomolecular Chemistry 22(42): 8374-8396. https://doi.org/10.1039/D4OB01259C
Faraj, S., Sequeira-Bisson, I. R., Lu, L., Miles-Chan, J. L., Hoggard, M., Barnett, D., Parry-Strong, A., Foster, M., Krebs, J. D., Poppitt, S. D., Taylor, M. W. & Mathrani, A. (2024). Effect of a higher-protein nut versus higher-carbohydrate cereal enriched diet on the gut microbiomes of Chinese participants with overweight and normoglycaemia or prediabetes in the Tū Ora study. Nutrients 16(12). https://doi.org/10.3390/nu16121971
Fellner, M., Randall, G., Bitac, I. R. C. G., Warrender, A. K., Sethi, A., Jelinek, R. & Kass, I. (2024). Similar but distinct—biochemical characterization of the staphylococcus aureus serine hydrolases FphH and FphI. Proteins: Structure, Function and Bioinformatics. https://doi.org/10.1002/prot.26785
Garelja, M. L., Alexander, T. I., Walker, C. S. & Hay, D. L. (2024). Extracellular bimolecular fluorescence complementation for investigating membrane protein dimerization: a proof of concept using class B GPCRs. Bioscience Reports 44(10). https://doi.org/10.1042/BSR20240449
Glyn, T., Williams, S., Whitehead, M., Eglinton, T., West, N. & Purcell, R. V. (2024). Digital spatial profiling identifies molecular changes involved in development of colitis-associated colorectal cancer. Frontiers in Oncology 14. https://doi.org/10.3389/fonc.2024.1247106
Gong, G. Q., Masson, G. R., Lee, W. J., Dickson, J. M. J., Kendall, J. D., Rathinaswamy, M. K., Buchanan, C. M., Middleditch, M., Owen, B. M., Spicer, J. A., Rewcastle, G. W., Denny, W. A., Burke, J. E., Shepherd, P. R., Williams, R. L. & Flanagan, J. U. (2024). ATP-competitive inhibitors of PI3K enzymes demonstrate an isoform selective dual action by controlling membrane binding. Biochemical Journal 481(23): 1787-1802. https://doi.org/10.1042/BCJ20240479
Hale, S. J. M., Cameron, A. J., Lux, C. A., Biswas, K., Kim, R., O'Carroll, M., Harris, P. W. R., Douglas, R. G. & Mackenzie, B. W. (2024). Polymyxin B and ethylenediaminetetraacetic acid act synergistically against Pseudomonas aeruginosa and Staphylococcus aureus. Microbiology Spectrum 12(2). https://doi.org/10.1128/spectrum.01709-23
Hay, D. L. (2024). A future treatment horizon for migraine? The Lancet Neurology 23(3): 226-227. https://doi.org/10.1016/s1474-4422(24)00032-2
Hills, F. R., Eruera, A. R., Hodgkinson-Bean, J., Jorge, F., Easingwood, R., Brown, S. H. J., Bouwer, J. C., Li, Y. P., Burga, L. N. & Bostina, M. (2024). Variation in structural motifs within SARSrelated coronavirus spike proteins. PLoS Pathogens 20(5), e1012158. https://doi.org/10.1371/journal.ppat.1012158
Hong, C. R., Liew, L. P., Wong, W. W., Dickson, B. D., Cheng, G., Shome, A., Airey, R., Jaiswal, J., Lipert, B., Jamieson, S. M. F., Wilson, W. R. & Hay, M. P. (2024). Identification of 6-anilino imidazo[4,5-c]pyridin-2-ones as selective DNA-dependent protein kinase inhibitors and their application as radiosensitizers. Journal of Medicinal Chemistry 67(14): 12366-12385. https://doi.org/10.1021/acs.jmedchem.4c01120
Hossain, S. M., Carpenter, C. & Eccles, M. R. (2024). Genomic and epigenomic biomarkers of immune checkpoint immunotherapy response in melanoma: Current and future perspectives. International Journal of Molecular Sciences 25(13). https://doi.org/10.3390/ijms25137252
Long, D., Eade, L., Sullivan, M. P., Dost, K., Meier-Menches, S. M., Goldstone, D. C., Hartinger, C. G., Wicker, J. S. & Taškova, K. (2024). AdductHunter: identifying protein-metal complex adducts in mass spectra. Journal of Cheminformatics 16(1). https://doi.org/10.1186/s13321-023-00797-7
Lorenz, N., James, A., Van Rooyen, T., Paterson, A., Ramiah, C., Carlton, L. H., Sharma, P., Baker, M. G., Charlewood, R., McGregor, R. & Moreland, N. J. (2025). Decline of antibodies to major viral and bacterial respiratory pathogens during the COVID-19 pandemic. The Journal of Infectious Diseases 231(1): e77-e81. https://doi.org/10.1093/infdis/jiae611
Major, T. J., Takei, R., Matsuo, H., Leask, M. P., Sumpter, N. A., Topless, R. K., Shirai, Y., Wang, W., Cadzow, M. J., Phipps-Green, A. J., Li, Z., Ji, A., Merriman, M. E., Morice, E., Kelley, E. E., Wei, W. H., McCormick, S. P. A., Bixley, M. J., Reynolds, R. J., Saag, K. G., Fadason, T., Golovina, E., O’Sullivan, J. M., Stamp, L. K., Dalbeth, N., Abhishek, A., Doherty, M., Roddy, E., Jacobsson, L. T. H., Kapetanovic, M. C., Melander, O., Andrés, M., Pérez-Ruiz, F., Torres, R. J., Radstake, T., Jansen, T. L., Janssen, M., Joosten, L. A. B., Liu, R., Gaal, O. I., Crişan, T. O., Rednic, S., Kurreeman, F., Huizinga, T. W. J., Toes, R., Lioté, F., Richette, P., Bardin, T., Ea, H. K., Pascart, T., McCarthy, G. M., Helbert, L., Stibůrková, B., Tausche, A. K., Uhlig, T., Vitart, V., Boutin, T. S., Hayward, C., Riches, P. L., Ralston, S. H., Campbell, A., MacDonald, T. M., Nakayama, A., Takada, T., Nakatochi, M., Shimizu, S., Kawamura, Y., Toyoda, Y., Nakaoka, H., Yamamoto, K., Matsuo, K., Shinomiya, N., Ichida, K., Lee, C., Bradbury, L. A., Brown, M. A., Robinson, P. C., Buchanan, R. R. C., Hill, C. L., Lester, S., Smith, M. D., Rischmueller, M., Choi, H. K., Stahl, E. A., Miner, J. N., Solomon, D. H., Cui, J., Giacomini, K. M., Brackman, D. J., Jorgenson, E. M., Liu, H., Susztak, K., Shringapure, S., Shringarpure, S., So, A., Okada, Y., Li, C., Shi, Y. & Merriman, T. R. (2024). Correction to: A genome-wide association analysis reveals new pathogenic pathways in gout (Nature Genetics, (2024), 56, 11, (2392-2406), 10.1038/s41588-024-01921-5). Nature Genetics 56(11): 2577. https://doi.org/10.1038/s41588-024-02017-w
Major, T. J., Takei, R., Matsuo, H., Leask, M. P., Sumpter, N. A., Topless, R. K., Shirai, Y., Wang, W., Cadzow, M. J., Phipps-Green, A. J., Li, Z., Ji, A., Merriman, M. E., Morice, E., Kelley, E. E., Wei, W. H., McCormick, S. P. A., Bixley, M. J., Reynolds, R. J., Saag, K. G., Fadason, T., Golovina, E., O’Sullivan, J. M., Stamp, L. K., Dalbeth, N., Abhishek, A., Doherty, M., Roddy, E., Jacobsson, L. T. H., Kapetanovic, M. C., Melander, O., Andrés, M., Pérez-Ruiz, F., Torres, R. J., Radstake, T., Jansen, T. L., Janssen, M., Joosten, L. A. B., Liu, R., Gaal, O. I., Crişan, T. O., Rednic, S., Kurreeman, F., Huizinga, T. W. J., Toes, R., Lioté, F., Richette, P., Bardin, T., Ea, H. K., Pascart, T., McCarthy, G. M., Helbert, L., Stibůrková, B., Tausche, A. K., Uhlig, T., Vitart, V., Boutin, T. S., Hayward, C., Riches, P. L., Ralston, S. H., Campbell, A., MacDonald, T. M., Nakayama, A., Takada, T., Nakatochi, M., Shimizu, S., Kawamura, Y., Toyoda, Y., Nakaoka, H., Yamamoto, K., Matsuo, K., Shinomiya, N., Ichida, K., Lee, C., Bradbury, L. A., Brown, M. A., Robinson, P. C., Buchanan, R. R. C., Hill, C. L., Lester, S., Smith, M. D., Rischmueller, M., Choi, H. K., Stahl, E. A., Miner, J. N., Solomon, D. H., Cui, J., Giacomini, K. M., Brackman, D. J., Jorgenson, E. M., Liu, H., Susztak, K., Shringapure, S., Shringarpure, S., So, A., Okada, Y., Li, C., Shi, Y. & Merriman, T. R. (2024). A genome-wide association analysis reveals new pathogenic pathways in gout. Nature Genetics 56(11): 2392-2406. https://doi.org/10.1038/s41588-024-01921-5
Mazzini, G., Le Foll, C., Boyle, C. N., Garelja, M. L., Zhyvoloup, A., Miller, M. E. T., Hay, D. L., Raleigh, D. P. & Lutz, T. A. (2024). The processing intermediate of human amylin, pro-amylin(1–48), has in vivo and in vitro bioactivity. Biophysical Chemistry 308. https://doi.org/10.1016/j.bpc.2024.107201
McCone, J. A. J., Teesdale-Spittle, P. H., Flanagan, J. U. & Harvey, J. E. (2024). A structure-activity investigation of the fungal metabolite (−)-TAN-2483B: Inhibition of Bruton's tyrosine kinase. Chemistry - A European Journal 30(35). https://doi.org/10.1002/chem.202401051
McSweeney, A. M., Eruera, A. R., McKenzie-Goldsmith, G. M., Bouwer, J. C., Brown, S. H. J., Stubbing, L. A., Hubert, J. G., Shrestha, R., Sparrow, K. J., Brimble, M. A., Harris, L. D., Evans, G. B., Bostina, M., Krause, K. L. & Ward, V. K. (2024). Activity and cryo-EM structure of the polymerase domain of the human norovirus ProPol precursor. Journal of Virology 98(11). https://doi.org/10.1128/aac.02799-13
Na, T. U., Sander, V., Davidson, A. J., Lin, R., Hermant, Y. O., Hardie Boys, M. T., Pletzer, D., Campbell, G., Ferguson, S. A., Cook, G. M., Allison, J. R., Brimble, M. A., Northrop, B. H. & Cameron, A. J. (2024). Allenamides as a powerful tool to incorporate diversity: Thia-Michael lipidation of semisynthetic peptides and access to β-keto amides. Angewandte Chemie - International Edition 63(39). https://doi.org/10.1002/anie.202407764
Osowicki, J., Frost, H. R., Azzopardi, K. I., Whitcombe, A. L., McGregor, R., Carlton, L. H., Baker, C., Fabri, L., Pandey, M., Good, M. F., Carapetis, J. R., Walker, M. J., Smeesters, P. R., Licciardi, P. V., Moreland, N. J., Hill, D. L. & Steer, A. C. (2024). Streptococcus pyogenes pharyngitis elicits diverse antibody responses to key vaccine antigens influenced by the imprint of past infections. Nature Communications 15(1). https://doi.org/10.1038/s41467-024-54665-5
Palpal-Latoc, D., Horsfall, A. J., Cameron, A. J., Campbell, G., Ferguson, S. A., Cook, G. M., Sander, V., Davidson, A. J., Harris, P. W. R. & Brimble, M. A. (2024). Synthesis, structure-activity relationship study, bioactivity, and nephrotoxicity evaluation of the proposed structure of the cyclic lipodepsipeptide brevicidine B. Journal of Natural Products 87(4): 764-773. https://doi.org/10.1021/acs.jnatprod.3c00876
Park, S. M., Chen, C. J. J., Verdon, D. J., Ooi, M. P. Y., Brooks, A. E. S., Martin, R. C. W., Mathy, J. A., Emanuel, P. O. & Dunbar, P. R. (2024). Proliferating macrophages in human tumours show characteristics of monocytes responding to myelopoietic growth factors. Frontiers in Immunology 15. https://doi.org/10.3389/fimmu.2024.1412076
Randall, G. T., Grant-Mackie, E. S., Chunkath, S., Williams, E. T., Middleditch, M. J., Tao, M., Harris, P. W. R., Brimble, M. A. & Bashiri, G. (2024). A stable dehydratase complex catalyzes the formation of dehydrated amino acids in a class v lanthipeptide. ACS Chemical Biology 19(12): 2548-2556. https://doi.org/10.1021/acschembio.4c00637
Ray Das, S., Delahunt, B., Lasham, A., Li, K., Wright, D., Print, C., Slatter, T., Braithwaite, A. & Mehta, S. (2024). Combining TP53 mutation and isoform has the potential to improve clinical practice. Pathology 56(4): 473-483. https://doi.org/10.1016/j.pathol.2024.02.003
Rees, T. A., Buttle, B. J., Tasma, Z., Yang, S. H., Harris, P. W. R. & Walker, C. S. (2024). Tirzepatide, GIP(1-42) and GIP(1-30) display unique signaling profiles at two common GIP receptor variants, E354 and Q354. Frontiers in Pharmacology 15. https://doi.org/10.3389/fphar.2024.1463313
Rees, T. A., Tasma, Z., Garelja, M. L., O’Carroll, S. J., Walker, C. S. & Hay, D. L. (2024). Calcitonin receptor, calcitonin gene-related peptide and amylin distribution in C1/2 dorsal root ganglia. Journal of Headache and Pain 25(1). https://doi.org/10.1186/s10194-024-01744-z
Rizwan, M. Z., Kamstra, K., Pretz, D., Shepherd, P. R., Tups, A. & Grattan, D. R. (2024). Conditional deletion of β-Catenin in the mediobasal hypothalamus impairs adaptive energy expenditure in response to high-fat diet and exacerbates diet-induced obesity. Journal of Neuroscience 44(14). https://doi.org/10.1523/jneurosci.1666-23.2024
Rousseau, M., Oulavallickal, T., Williamson, A., Arcus, V., Patrick, W. M. & Hicks, J. (2024). Characterisation and engineering of a thermophilic RNA ligase from Palaeococcus pacificus. Nucleic Acids Research 52(7): 3924-3937. https://doi.org/10.1093/nar/gkae149
Shepperson, O. A., Harris, P. W. R., Brimble, M. A. & Cameron, A. J. (2024). The antimicrobial peptide capitellacin: Chemical synthesis of analogues to probe the role of disulphide bridges and their replacement with vinyl sulphides. Antibiotics 13(7). https://doi.org/10.3390/antibiotics13070615
Shepperson, O. A., Harris, P. W. R., Brimble, M. A. & Cameron, A. J. (2024). Thanatin and vinyl sulfide analogues as narrow spectrum antimicrobial peptides that synergise with polymyxin B. Frontiers in Pharmacology 15. https://doi.org/10.3389/fphar.2024.1487338
Siow, A., Kowalczyk, R., Hong, J. & Harris, P. W. R. (2024). Chemical modifications on the αvβ6 integrin targeting A20FMDV2 peptide: A review. ChemMedChem 19(18). https://doi.org/10.1002/cmdc.202400131
Spicer, J., Jose, J., Lee, W. J., Rickard, S. & Flanagan, J. (2024). Synthesis and biological characterisation of a des-aza-dasatinib tool compound. Tetrahedron Letters 138. https://doi.org/10.1016/j.tetlet.2024.154940
Takahashi, R., J-Khemlani, A. H., Loh, J. M. S., Radcliff, F. J., Proft, T. & Tsai, C. J. Y. (2024). Different Group A Streptococcus pili lead to varying proinflammatory cytokine responses and virulence. Immunology and Cell Biology 102(1): 21-33. https://doi.org/10.1111/imcb.12692
Tasma, Z., Rees, T. A., Guo, S., Tan, S., O'Carroll, S. J., Faull, R. L. M., Curtis, M. A., Christensen, S. L., Hay, D. L. & Walker, C. S. (2024). Pharmacology of PACAP and VIP receptors in the spinal cord highlights the importance of the PAC1 receptor. British Journal of Pharmacology 181(15): 2655-2675. https://doi.org/10.1111/bph.16376
Taylor, T. A., Beban, G., Yi, E., Veukiso, M., Sang-Yum, G., Dewes, O., Wrapson, W., Taufa, N., Campbell, A. R. T., Siegert, R. J. & Shepherd, P. (2024). Empowering pacific patients on the weight loss surgery pathway: A co-designed evaluation study. Obesity Surgery 34(3): 959-966. https://doi.org/10.1007/s11695-024-07084-w
Tong, J. T. W., Sarwar, M., Ahangarpour, M., Hume, P. A., Williams, G. M., Brimble, M. A. & Kavianinia, I. (2024). Use of a Cyclic α-Alkylidene-β-Diketone as a Cleavable Linker Strategy for Antibody-Drug Conjugates. Journal of the American Chemical Society 146(34): 23717-23728. https://doi.org/10.1021/jacs.4c04567
Topham, B., Hock, B., Phillips, E., Wiggins, G. & Currie, M. (2024). The role of innate priming in modifying tumor-associated macrophage phenotype. Frontiers in Bioscience - Landmark 29(12). https://doi.org/10.31083/j.fbl2912418
Tsai, C. J. Y. & Fujihashi, K. (2024). Mucosal vaccine delivery. Advanced vaccination technologies for infectious and chronic diseases: A guide to vaccinology, Academic Press: 207-224.
Tweedie-Cullen, R. Y., Jiang, Y., Brandon, R., Tay, A., Yeu, R., Smallman, K., Doherty, G., Dewes, O., Doran, R., Clark, P., Nehren, N., Hindmarsh, J. H., King, F., Merriman, T. R., Moffitt, A., Orr-Walker, B., Paul, R. & Murphy, R. (2024). Diabetes treatment satisfaction among a multi-ethnic Aotearoa New Zealand population with uncontrolled type 2 diabetes mellitus. New Zealand Medical Journal 137(1600): 66-75.https://doi.org/10.26635/6965.6341
Underwood, L., Teng, A., Bowden, N., Dewes, O., Marek, L. & Milne, B. (2024). Long-term health conditions among household families in Aotearoa New Zealand: cross-sectional analysis of integrated Census and administrative data. New Zealand Medical Journal 137(1596): 20-34. https://doi.org/10.26635/6965.6370
Vesty, A., Ren, X., Sharma, P., Lorenz, N., Proft, T., Hardaker, A., Straub, C., Morgan, J., Tiong, A., Anderson, A., Webb, R. H., Bennett, J., Carter, P. E. & Moreland, N. J. (2024). The emergence and impact of the M1UK lineage on invasive Group A Streptococcus disease in Aotearoa New Zealand. Open Forum Infectious Diseases 11(8). https://doi.org/10.1093/ofid/ofae457
Wang, Q., Leask, M. P., Lee, K., Jaiswal, J., Kallingappa, P., Dissanayake, W., Puli’uvea, C., O’Sullivan, C., Watson, H., Wilcox, P., Murphy, R., Merry, T. L. & Shepherd, P. R. (2024). The population-specific Thr44Met OCT3 coding variant affects metformin pharmacokinetics with subsequent effects on insulin sensitivity in C57Bl/6J mice. Diabetologia. https://doi.org/10.1007/s00125-024-06287-1
Wang, Q., McCormick, S., Leask, M. P., Watson, H., O'Sullivan, C., Krebs, J. D., Hall, R., Whitfield, P., Merry, T. L., Murphy, R. & Shepherd, P. R. (2024). A Polynesian-specific SLC22A3 variant associates with low plasma lipoprotein(a) concentrations independent of apo(a) isoform size in males. Bioscience Reports 44(7). https://doi.org/10.1042/bsr20240403
Yang, F., Lin, Q., Song, X., Huang, H., Chen, X., Tan, J., Li, Y., Zhou, Y., Tu, Z., Du, H., Zhang, Z. M., Ortega, R., Lin, X., Patterson, A. V., Smaill, J. B., Chen, Y. & Lu, X. (2024). Discovery of 6-Formylpyridyl urea derivatives as potent reversible-covalent fibroblast growth factor receptor 4 inhibitors with improved anti-hepatocellular carcinoma activity. Journal of Medicinal Chemistry 67(4): 2667-2689. https://doi.org/10.1021/acs.jmedchem.3c01810